Welcome to the Josselyn Frankland Lab
Neurobiology Laboratory at the Hospital for Sick Children

Research

Learning and Memory

Memory Allocation

How do neurons become allocated to a memory trace and how can we manipulate their activity to understand memory?

Remote Memory

How are remote memories organized in the cortex, and what the molecular and cellular events that underlie their consolidation?

Neurogenesis and Forgetting

What is the contribution of new neurons to hippocampal memory function. In particular we are interested in how new neurons regulate clearance of memories from the hippocampus (or forgetting).

Publications

Click for journal website.

Santos, Thays Brenner et al. (2024) Reactivation of encoding ensembles in the prelimbic cortex supports temporal associations. Neuropsychopharmacology.

Mocle, Andrew J et al. (2024) Excitability mediates allocation of pre-configured ensembles to a hippocampal engram supporting contextual conditioned threat in mice. Neuron.

Xie, Connie T Y et al. (2024) Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability. Cells, 13.

Scala, Marcello et al. (2023) Genetic variants in DDX53 contribute to Autism Spectrum Disorder associated with the Xp22.11 locus. medRxiv.

Jung, Jung Hoon et al. (2023) Examining memory linking and generalization using scFLARE2, a temporally precise neuronal activity tagging system. Cell Rep, 42, 12, 113592.


All Publications

Lab Members

Primary Investigators

Sheena Josselyn

PI

Paul Frankland

PI

Current Lab Members

Adam Ramsaran

PhD Candidate

Frankland
Newark, Delaware

    Interests:
  •  Womp it Up (Podcast)
  •  Veep
  •  HRC

Alessandro Luchetti

Post-Doc

Josselyn
Milan, Italy

Alex Jacob

PhD Candidate

Josselyn
Edmonton, AB

Ali Golbabaei

PhD Student

Frankland

Andrew Mocle

PhD Candidate

Josselyn
Toronto, ON

    Interests:
  •  Squash
  •  Melodica
  •  Too Much Tuna

Annelies Hoorn

PhD Student

Josselyn
The Netherlands

    Interests:
  •  :bee:
  •  Philosophy

Asim Rashid

Research Associate

Josselyn
Kingston, ON

Bozhi Wu

PhD Student

Josselyn
Shanghai, China

    Interests:
  •  Reading
  •  Photography
  •  Tennis
  •  Saxophone

Cory McKenzie

PhD Student

Frankland
Peace River, AB

    Interests:
  •  Cooking
  •  Bouldering
  •  Reading

Daisy Lin

Lab Technician
Beijing, China

Jenn Kao

MD/PhD

Frankland
Richmond Hill, ON

    Interests:
  •  Hockey (the leafs!)
  •  Night running
  •  Painting

Jiaoyang Wo

PhD Student

Frankland
Beijing, China

    Interests:
  •  Painting
  •  Reading
  •  Travelling
  •  Dancing

Joseph Lee

PhD Student

Josselyn
Toronto, ON

    Interests:
  •  Bass Guitar
  •  Music
  •  Observing Wildlife

Jung Hoon Jung

Post-Doc

Josselyn
Daegu, South Korea

    Interests:
  •  Movies
  •  Soccer
  •  Family

Marie-Theres Wittmann

Post-Doc

Frankland
Erlangen, Germany

    Interests:
  •  Baking
  •  Photography
  •  Reading

Matteo Saderi

PhD Student

Frankland
Sardinia, Italy

    Interests:
  •  Consciousness
  •  Volcanoes
  •  Astronomy

Meeraal Zaheer

PhD Student

Josselyn
Karachi, Pakistan

    Interests:
  •  Concerts
  •  Food
  •  Fitness

Meijia Li

PhD Student

Josselyn
Chengdu, China

    Interests:
  •  Baking
  •  Cooking
  •  Travelling
  •  Olfactory Art

Mika Yamamoto

Lab Technician
Osaka, Japan

Mitch de Snoo

MD/PhD

Frankland
Oshawa, ON

    Interests:
  •  Lacrosse
  •  Camping
  •  Food

Mitra Tayaranian

MSc Student

Frankland
Iran

    Interests:
  •  Animals :cat:
  •  Nature
  •  Photography
  •  Puzzels

Navvab Afrashteh

Post-Doc

Frankland
Dehdasht, Iran

    Interests:
  •  Soccer
  •  Reading
  •  Cooking
  •  Cultures and Languages

Rida Ansari

PhD Candidate

Frankland
Karachi, Pakistan

    Interests:
  •  :tropical_fish:

Sakthivel Srinivasan

Post-Doc

Frankland
Chennai, India

    Interests:
  •  Running
  •  Reading
  •  Investing

Sangyoon Ko

PhD Candidate

Frankland
Jeju, Korea

    Interests:
  •  Soccer
  •  Baseball
  •  Judo
  •  Music

Silvia Ventura

Post-Doc

Frankland
Rome, Italy

    Interests:
  •  Traveling
  •  Bouldering
  •  Philosophy

Sofiya Zbaranska

PhD Student

Josselyn
Kyiv, Ukraine

    Interests:
  •  Working Out
  •  Vegan Food
  •  Reading
  •  :butterfly:

Sungmo Park

Post-Doc

Josselyn
Seoul, Korea

    Interests:
  •  Photography
  •  Movie maker
  •  my kids

Toni DeCristofaro

Lab Manager
Toronto, ON

Wei (William) He

Lab Technician
Changchun, China

Xiaoyu Chen

PhD Student

Frankland
Chengdu, China

    Interests:
  •  Painting
  •  Photography
  •  Cooking
  •  Japanese Mahjong

Ying Wang

PhD Candidate

Josselyn
Nanjing, China

    Interests:
  •  basketball
  •  music
  •  food

Yunlong Liu

Post-Doc

Frankland
Beijing, China

    Interests:
  •  Neurogenesis
  •  Forgetting

Where are they now?

Check out this map of former Jossenlyn/Frankland lab members who have started their own labs around the world


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New Website

25 September 2018

Welcome to the new JF Lab website. It’s still undergoing some changes so feel free to let us know if you see any problems via our GitHub page. There, you can also see how this site was made.